Active Grants

Crabtree BF (PI), Hudson SV (Co-I), Cantor J (Co-I): (Subcontract) with University of Southern California Tsui J (PI), "Accelerating Evidence-based Strategies into Practice for HPV Vaccination in Safety-Net Primary Care Settings," R37CA242541, NCI. $750,000 [direct], $1,192,500 [total], 07/01/2021 – 04/30/2024.
This research will identify multilevel stakeholder perspectives on existing evidence-based strategies (EBS) targeted at the provider, clinic, and system levels and evaluate the implementation of EBS to increase HPV vaccination among adolescents (males and females) within safety-net primary care settings in New Jersey.

Delnevo C (MPI), Hrywna M (MPI), Hudson SV (Co-I): "Adoption, diffusion and implementation of Tobacco 21 policies to address health disparities," R01CA231139, NCI.  $1,865,647 [direct], $1,171,532 [indirect], $3,037,179 [total], 07/01/2018 – 06/30/2024.
Using the multiple streams policy and RE-AIM implementation science frameworks, this project uses a mixed methods approach to understand the implementation and impact of policies that raise the minimum legal access to tobacco age to 21, seeking to expand the evidence base with a focus on racial/ethnic groups in the context of a diverse tobacco environment.  Specifically, we: (1) carry out a comparative case study of 15 states using document analysis of Tobacco 21 bills, news media content analysis, and key informant interviews to identify factors that may contribute to the adoption or rejection of Tobacco 21 legislation; (2) conduct a repeated cross sectional tobacco product purchase study to examine implementation of a statewide Tobacco 21 law in New Jersey; and, (3) describe the impact of Tobacco 21 laws by modeling tobacco use behavior among 13 to 25 year old's in states with and without Tobacco 21 laws using data from the National Survey on Drug Use and Health.

Garland (contact PI); Cooperman (MPI), Ferrante J (Co-I). “Optimizing Patient-Centered Opioid Tapering with Mindfulness-Oriented Recovery Enhancement,” NIDA R01DA058621, $1,178,168 [annual], $5,743,192 [total], 08/15/2023 – 08/14/2028.
The goal of this proposed study is to conduct a hybrid 2 implementation-effectiveness trial of MORE (Mindfulness-Oriented Recovery Enhancement) plus patient-centered opioid tapering in primary care for patients with chronic pain to reduce opioid-misuse, decrease chronic pain, while improving mental health and quality of life.

Heckman C (PI), Hudson SV (Co-I).  "A Multi-Level Investigation of US Indoor Tanning Policy Enactment, Implementation, Compliance, Impact, and Economics," R01CA244370, NCI.  $2,953,004 [direct], $830,535 [indirect], $3,783,539 [total], 07/01/2020 – 06/30/2025. ***Impact Score 17, 2nd percentile***
The goals of this 5-year R01 are to use a mixed-method approach informed by the Multiple [Policy] Streams (MSF) and RE-AIM, Frameworks to investigate the following Specific Aims related to policy adoption, implementation (e.g., compliance), and maintenance (i.e., sustainability) to guide policy efforts and decrease IT prevalence.

Hudson SV (PI), "Interprofessional Assignment (IPA) Agreement with National Cancer Institute (NCI)" NCI. $12,981 [total], 11/01/2022 – 10/31/2023.
NCI's Office of Cancer Survivorship has been a leader in supporting extramural research and leading intramural initiatives to support research that promotes a better understanding of the unique needs of the growing population of cancer survivors and to enhance our ability to address them.  This IPA would serve as a liaison between NIH, NCI, the NCI Primary Care Working Group, and the grantee community to seek feedback and provide expertise on gaps and opportunities that can directly inform NCI efforts.

Hudson, SV (MPI), Crabtree, BF (MPI), Ferrante, JM (Co-I), "Adapting and implementing evidence-based breast cancer follow-up," R01CA257197, NCI. $3,919,583 [total], 07/01/2021 – 06/30/2026.
Using a blended implementation/primary care practice change conceptual framework, this project aims to: (1) engage diverse primary care stakeholders in identifying actionable, practice-based activities for provision of long-term breast cancer survivorship care in primary care using depth interviews; (2) prioritize, synthesize, and identify actionable activities for providing care to long-term cancer survivors in primary care by engaging key stakeholders using modified online Delphi methods and concept mapping; and (3) implement and evaluate actionable breast cancer survivorship symptom and risk management activities using a hybrid type 1 effectiveness-implementation cluster study design with waitlist control in 26 primary care practices

Jensen JK (PI). “The Impact of Cigar Pack Quantity on Tobacco Use Behaviors,” K01CA235253, NCI/FDA. $964,911 [total], 07/01/2020 – 06/30/2025.
The goals of the study are to advance understanding of the relationship between cigar pack quantity and tobacco use behaviors to inform regulation on minimum cigar pack quantity. We aim to assess whether cigar pack quantity is associated with between- and within-person changes in cigar, identify the impact of local minimum cigar pack quantity laws on cigar and other tobacco use and cigar sales, and characterize differences in the implementation and enforcement of minimum cigar pack quantity.

Jiang Y (PI). "Racial residential segregation and inflammation in older African Americans." Michigan Center for Urban African American Aging Research.  $26,999 [total] 07/01/2022 – 06/30/2024.
This project aims to investigate the intermediate processes through which racial residential segregation affects systemic inflammation in a sample of older African Americans living in Detroit.

Jiang Y (PI). Social isolation, depression, and cardiovascular health among older Chinese immigrants.  Rutgers-New York University Center for Asian Health Promotion and Equity Pilot Grant. $25,000 [total], 06/15/2022 – 05/31/2024.
This project aims to investigate how daily solitude affects daily blood pressure and depressive affect via daily salivary cortisol secretion in a sample of Chinese immigrants living in New Jersey.

Jiang Y (PI), Chung T, and Wu B. "Daily psychosocial stress and cardiometabolic health of older Chinese Americans." NIMHD $440,113 [total], 06/12/2023 – 12/31/2024.
The goal of this project is to investigate the biopsychological processes through which daily interpersonal stressors affect cardiometabolic health, and how sociocultural factors shape these associations in a sample of older Chinese immigrants.

Jimenez M (PI), Crabtree BF (Co-I), and Hudson SV (Co-I), "Addressing Disparities in Language and Social-emotional Skill Acquisition using Multi-Level Strategies in Primary Care," R01HD099125, NICHD. $3,637,203 [total], 05/15/2020 – 02/28/2025.
A 3-arm randomized clinical trial (RCT) is proposed to test strategies designed to address these barriers using individual and community level interventions. We will recruit 630 parent-child dyads from community health centers that serve low-income Latino families. Parents will be randomly assigned to one of 3 arms (1) A standard evidence-based literacy promotion intervention that is widely disseminated (2) Literacy promotion plus tailored outreach text messages; (3) Literacy promotion plus tailored outreach text messages and material hardship screening with linkage to community-based resources (multi-level strategy).

Jimenez ME (PI), Crabtree BF (Co-I), and Hudson SV (Co-I), "Ready and Healthy for Kindergarten: A Primary Care Innovation to Promote a 360-degree View of Child Health," R18HS028574, AHRQ. $1,986,472 [total], 12/01/2021 – 11/30/2026.
This study will test an innovative family wellness program that promotes academic and physical readiness for school among Latino dual language learners using a rigorous mixed methods and community engaged approach.

Luth EA (PI). "Enhancing Dementia Instruction and Tool in Home Hospice (EDITH-HC)," R00AG065624, NIA. $746,200 [total], 09/01/2021 – 08/31/2024.
This study develops and pilot tests an educational intervention and support tool for hospice nurses and social workers to reduce stress and burden in family care partners of home hospice patients living with dementia.

Luth EA (PI); Bowles K (co-PI). "Translating Data Science to Palliative Care Practice: Improving Integration of a Claims-Based Algorithm and Palliative Care Uptake." NJ ACTS Pilot Program-Value Partnership Grant. $50,000 [total], 03/01/23 – 02/28/24.
The overall objectives of this project are to identify barriers to incorporating algorithm-developed mortality data into clinical and healthcare decision making and develop improved algorithms for distinguishing community-based palliative care-eligible individuals.

Luth EA (PI), Bowles K, Brickner C. “Translating Data Science to Palliative Care Practice for Persons Living with Dementia.” UPenn Roybal Center Pilot Grant Program, $100,000 [total], 10/01/2023 – 09/30/2024.
The overall objective of this grant is to understand reasons palliative care-eligible individuals refuse the service and develop materials for palliative care clinicians (RNs, NPs) to present palliative care to eligible individuals based on individualized mortality risk.

Manne S (PI), Hudson SV (Co-I), "Enhancing Self Care Among Oral Cancer Survivors: The Empowered Survivor Trial," R01CA240344, NCI. $3,729,269 [total], 03/15/2020 – 02/28/2025.
The goal of the proposed single site clinical trial study is to evaluate the impact of Empowered Survivor against a Generic Online intervention on the primary outcomes of self-efficacy in managing care, preparedness for managing survivorship, and health-related QOL.

Menifield C (PI), Wade MJ (PI), Hill D, Hudson SV (Subcontract), "Advancing Health Literacy to Enhance Equitable Community Responses to COVID-19", HHS/OMH. $500,000 [total] 07/01/2021 – 12/31/2023.
The award seeks to demonstrate the effectiveness of local "grass roots" implementation of culturally appropriate, evidence-based health literacy strategies to enhance COVID-19 testing, contact tracing and/or other mitigation measures in socially vulnerable populations.  The Rutgers team will engage in quality improvement and evaluation activities.

Miller (contact MPI), Hudson SV (MPI), Wen (MPI). "Reducing Urban Cervical Cancer Disparities Using a Tailored mHealth Intervention to Enhance Colposcopy Attendance," R01MD017675, NIMHD. $4,139,634 [total] $1,185,749 [Rutgers total], 07/15/2023 – 12/31/2027.
This project will develop and evaluate a novel, theory-based mHealth intervention available in both English and Spanish consisting of patient focused text-based barriers counseling and as-needed telephone health coaching thereby increasing long-term follow-up rates among urban, underserved minority women.

Nguyen AM (PI). "Analysis of the size, composition, geographic distribution and engagement of New Jersey’s perinatal workforce.” NJ Department of Human Services. $250,000 [total], 04/01/2023 – 10/31/2023.
The scope of this project is to conduct a landscape analysis, using publicly available data, of the perinatal workforce in New Jersey. The analysis will focus on four key provider workforce segments that have bearing on maternal health in the state: Ob/Gyns, midwives, doulas, and community healthcare workers. This landscape analysis is designed to answer critical questions about the size, composition, geographic distribution, and engagement of the perinatal workforce in the state with the purpose of informing future strategic planning and program development in New Jersey.

O'Malley DM (PI), "Optimizing Colorectal Cancer Screening among Patients with Diabetes in Safety-Net Primary Care Settings: Targeting Implementation Approaches," K99CA256043-01/R00, NCI. $1,063,928 [total], $1,040,452 [total direct], $23,476 [indirect], 12/01/2020 – 11/30/2025.
Patients with diabetes diagnosed with colorectal cancer are at high risk for excess morbidity and mortality and are disproportionately Non-Hispanic Black and Hispanic. Federally qualified health centers, who primarily serve priority populations, struggle to implement and sustain colorectal cancer screening. This study proposes to identify and overcome multi-level factors affecting optimal use of CRC preventive screening options for patients with elevated medical and social risks throughout the U.S.

Pace and Mauger (MPI), Kleinman L (subcontract PI), Ferrante J (subcontract Co-I).  "Individualized Treatment for Asthma in Primary Care (iTREAT)" PCORI. $1,353,801 [total request], 01/01/2023 – 06/30/2029.
This study will compare the effectiveness of 5 different treatment options versus control in treatment of asthma. The options are inhaled corticosteroids as part of rescue therapy, azithromycin long term (> 6 months) to improve overall asthma control, a smart phone application to improve asthma medication compliance and tracking of symptoms and each of the medication arms plus the smart phone app

Panettieri R (PI), Core C. Project Leads: Hudson SV and Tallia A (C. Community and Collaboration) Core Advisor Crabtree BF, NJPCRN lead Ferrante JM. "National Institutes of Health, New Jersey Alliance for Clinical and Translational Science:  NJ ACTS," UL1TR003017, NCATS. $645,968 [core direct], 03/11/2019 – 02/29/2024.
The Community and Collaboration Core of NJ ACTS enhances and encourages community engagement and team science that will address critical health and healthcare issues in the population of New Jersey. Our community engagement strategies consist of: (1) engaging community stakeholders in research by developing and providing infrastructure to connect and train NJ academic and community partners and creating a technical assistance core for stakeholder engaged translational science; and (2) facilitating knowledge transfer regarding innovative community engagement methods and practices.   

Tang F (PI), Jiang Y (subcontract PI). “Preventing cognitive decline and dementia among older Chinese immigrants: The role of activity, engagement, immigration Experience, and neighborhood environments”. NIA $2,223,556 [total], 06/01/2020 – 03/31/2024.
The aim of this study is to conduct a secondary data analysis to examine key neighborhood, psychosocial, and cultural factors contributing to cognitive decline among older Chinese immigrants.